Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders
Filippo Erli, Alish Palmos, Pooja Raval, Jayanta T. Mukherjee, Katherine J. Sellers, Nicholas J. F. Gatford, Stephen J. Moss, Nicholas J. Brandon, Peter Penzes, Deepak P. Srivastava
This study shows that estradiol restores dendritic spine density in a cellular model of schizophrenia and depression by modulating DISC1 function and synaptic protein distribution.
Translational Psychiatry · Jan 21, 2020Peer-reviewedNeuroscience