Pooja Raval

This study shows estradiol increases local synaptic protein synthesis in both sexes, but mTOR signaling is sex-specifically required for certain synaptic proteins.

The paper shows that schizophrenia hiPSC-derived NPCs have a reduced transcriptional response to IFN-gamma compared to controls, with implications for synaptic development and mitochondrial genes.

This study shows that NLGN3/4X clustering at growth cones promotes neuritogenesis and actin organization in immature human neurons, with ASD-associated variants lacking these effects.

This study shows ZNF804A and NT5C2 interact at synapses in cortical neurons, suggesting they function as a complex in schizophrenia risk.

This study shows that estradiol restores dendritic spine density in a cellular model of schizophrenia and depression by modulating DISC1 function and synaptic protein distribution.

This study shows that estradiol induces afadin trafficking between synaptic and nuclear compartments, which is required for histone H3 phosphorylation at serine 10.