Author
Memorial University of NewfoundlandORCID 0000-0003-0728-2269Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jessica C. Barron, Meghan L. Greenland, Samantha J. Carew…·Matthew P. Parsons
This study shows that loss of wild-type huntingtin in adult striatal neurons reduces excitability and causes neuroinflammation without affecting tissue structure or motor behavior.
Anusha Kamesh, Chelsie Kadgien, Naila Kuhlmann…·Austen J. Milnerwood
This study shows that VPS35(D620N) mutation leads to increased glutamate and dopamine transmission in mice, which can be reversed by LRRK2 inhibition.
Emily P. Hurley, Bandhan Mukherjee, Lisa Z. Fang…·Matthew P. Parsons
This study shows that GluN3A persistence in the adult ventral hippocampus reduces glutamate release and NMDAR-dependent long-term potentiation, impacting emotional processing.
Kyle J. Brymer, Emily P. Hurley, Jessica C. Barron…·Matthew P. Parsons
The paper shows that GLT-1 dysfunction disproportionately affects presynaptic glutamate clearance in an Alzheimer's mouse model, highlighting presynaptic vulnerability.