Non-canonical function of ADAM10 in presynaptic plasticity
Julia Bär, Tomas Fanutza, Christopher C. Reimann, Lisa Seipold, Maja Grohe, Janike Rabea Bolter, Flemming Delfs, Michael Bucher, Christine E. Gee, Michaela Schweizer, Paul Säftig, Marina Mikhaylova
This study identifies ADAM10's localization to presynaptic vesicles and shows its role in synaptic facilitation through interaction with synaptotagmin 7, independent of its proteolytic activity.
bioRxiv · May 12, 2024 · PreprintNeuroscience