Marina Mikhaylova

The paper characterizes the molecular architecture of somatic spines in the lateral septum across developmental stages using imaging techniques and cultured models.

This study shows that queuosine (Q) modification of tRNA enhances neuronal development and synaptic activity in cultured rat cortical neurons.

This study identifies Vaultrc5 as a noncoding RNA that regulates synaptic vault trafficking and RNA cargo dynamics, impacting learning and memory.

The paper shows that the SHANK3-CAMSAP2 interaction links synapses to dendritic microtubule organisation in parvalbumin neurons, with the SHANK3L68P mutation enhancing this interaction and altering microtubule dynamics.

The paper investigates the structural and functional differences between shaft and spine synapses, finding that shaft synapses are less stable and more responsive to activity changes.

This study shows that mTORC1-dependent translation in layer 5b neurons is essential for memory consolidation through activity-dependent plasticity.

This study investigates the developmental program and functional properties of axon-carrying-dendrite neurons, revealing unique features of their axon initial segment.

This study identifies ADAM10's localization to presynaptic vesicles and shows its role in synaptic facilitation through interaction with synaptotagmin 7, independent of its proteolytic activity.

The paper investigates the presence and dynamic behavior of Golgi satellites in axons, showing they are transported bidirectionally and pause at presynaptic sites regulated by neuronal activity and myosin VI.

The paper shows that disrupting the balance of microtubule tyrosination and detyrosination in neurons leads to defects in axonal transport and AIS length.

This study identifies KIF21B's role in regulating actin dynamics and AMPA receptor removal in dendritic spines during homeostatic synaptic downscaling.

The paper uses optogenetic stimulation to induce spike-timing-dependent plasticity (STDP) and shows that late potentiation occurs regardless of spiking order, but requires ongoing activity.

The paper shows that ligands binding to PrPC induce its proteolytic release, which has neuroprotective effects, and identifies mechanisms and exceptions in this process.

This study shows two ASD-associated SHANK3 mutations cause structural changes and altered protein turnover at synapses.

The paper shows that synaptic ER stabilization depends on calmodulin and caldendrin regulating myosin V activity to control spine apparatus formation in active dendritic spines.

This study identifies CAP2 as a regulator of Cofilin in synaptic plasticity, showing its role in LTP and its disruption in Alzheimer’s disease.

The paper shows radial F-actin organization around the centrosome during early neuronal development, with dynamic actin structures and interactions with centrosomal components.

The paper shows that actin patches at glutamatergic synapses create physical barriers that stall lysosome transport in dendrites.

This study identifies myosin V as essential for synaptopodin clustering at post-synaptic sites, showing that the spine apparatus is assembled locally rather than transported.