Christine E. Gee

The paper investigates the molecular mechanisms of early and late long-term potentiation (LTP) by manipulating CaMKII activity and shows that L-LTP can occur without CaMKII activation.

The paper investigates the interaction between Ca2+ and cAMP signaling in mouse olfactory bulb astrocytes, showing how different adrenergic receptors modulate these pathways.

The paper investigates how astrocytes respond to bottom-up and top-down neuronal activity in the olfactory bulb, finding that top-down input from the anterior piriform cortex drives astrocytic Ca²+ signaling through sustained GC firing.

The paper induces spike-timing-dependent plasticity in hippocampal synapses using optogenetics and performs ultrastructural analysis with transmission electron microscopy.

This paper introduces new organellar Ca2+ sensors with tunable colors and improved brightness and photostability for multiplexed measurements in different organelles.

This study develops a K+-selective channelrhodopsin for transcranial optogenetic inhibition of neuronal activity, showing reduced seizure activity in mouse models.

This study identifies ADAM10's localization to presynaptic vesicles and shows its role in synaptic facilitation through interaction with synaptotagmin 7, independent of its proteolytic activity.

The paper investigates how {Delta}FosB inhibition affects cFos expression and memory formation, finding that epigenetic repression of cFos supports sequential spatial memory formation.

The paper investigates the relationship between neuronal spiking frequency and FOS expression in hippocampal neurons, finding that FOS expression is cell-type specific, frequency-dependent, and not cell-autonomous.

This study identifies KIF21B's role in regulating actin dynamics and AMPA receptor removal in dendritic spines during homeostatic synaptic downscaling.

This study shows that katanin, a microtubule-severing complex, is located at dendritic spines and regulates microtubule polymerization and synaptic plasticity through activity-dependent processes.

The paper uses optogenetic stimulation to induce spike-timing-dependent plasticity (STDP) and shows that late potentiation occurs regardless of spiking order, but requires ongoing activity.

This paper introduces a variational image restoration method for low-SNR live cell Ca2+ fluorescence microscopy data, demonstrating its effectiveness across synthetic and biological datasets.

The paper shows that cFos expression in the dentate gyrus changes daily and does not stabilize with spatial memory, yet neurons from early training days still influence later performance.

The paper introduces SynTagMA, a tool to mark active synapses in a 2-second window, and provides software for analyzing large datasets of synaptic activity.

This study shows dopamine modulates ECM integrity at excitatory synapses via D1 receptors and proteases ADAMTS-4/5, affecting brevican and aggrecan cleavage.

The paper shows that the sequence of plasticity-inducing events in hippocampal synapses affects their survival, with later protocols having a dominant effect.