Oxytocin administration in neonates shapes the hippocampal circuitry and restores social behavior in a mouse model of autism.
Alessandra Bertoni, Fabienne Schaller, Roman Tyzio, Stéphane Gaillard, Francesca Santini, Marion Xolin, Diabé Diabira, Radhika Vaidyanathan, Valery A. Matarazzo, Igor Medina, Elizabeth A. D. Hammock, Jinwei Zhang, Bice Chini, Jean‐Luc Gaïarsa, Françoise Muscatelli
This study shows that oxytocin administration in neonatal Magel2-deficient mice restores hippocampal circuitry and social memory, suggesting therapeutic potential for autism.
Molecular Psychiatry · Jul 21, 2021Peer-reviewedNeuroscience