Jinwei Zhang

This study investigates how pro- and mature BDNF regulate chloride homeostasis via KCC2 in rat neurons, showing their distinct roles in inhibitory neurotransmission and developmental behavior.

This paper determines the crystal structure of KLHL3 in complex with a WNK3 peptide, revealing structural features and phosphorylation-dependent regulation of WNK3 binding.

This study shows that oxytocin administration in neonatal Magel2-deficient mice restores hippocampal circuitry and social memory, suggesting therapeutic potential for autism.

The paper shows that intracellular chloride levels in cortical pyramidal cells vary diurnally, affecting neuronal network stability and seizure latency.

This study shows that Smo signaling regulates the shift of GABA polarity in rat somatosensory cortex by controlling KCC2 stability and chloride homeostasis.

This study shows that impaired KCC2 phosphorylation in mice leads to neuronal network dysfunction and neurodevelopmental issues, with some effects reversible by bumetanide treatment.