Fabienne Schaller

Inhibition of oxytocin neurons during key periods of development has long-term behavioural and body composition effects.

This study inhibits oxytocin neurons during different developmental stages in mice, revealing long-term behavioral and metabolic effects depending on timing and sex.

The oxytocin-modulated brain circuit that synchronizes heart rate with breathing

This paper identifies a hypothalamus-brainstem circuit mediated by oxytocin that enhances respiratory sinus arrhythmia during calming behaviors.

Vesicle-mediated oxytocin release drives melanocortin circuit maturation during a neonatal critical period

This study shows that oxytocin release during a neonatal critical period is essential for melanocortin circuit development and metabolic function.

Investigation of a Novel Mouse Model of Prader-Willi Syndrome with Invalidation of Necdin and Magel2

This study creates a novel mouse model with deletion of Necdin and Magel2 genes, revealing functional interactions and phenotypes relevant to Prader-Willi Syndrome.

Oxytocin administration in neonates shapes the hippocampal circuitry and restores social behavior in a mouse model of autism.

This study shows that oxytocin administration in neonatal Magel2-deficient mice restores hippocampal circuitry and social memory, suggesting therapeutic potential for autism.

The Impact of Oxytocin on Neurite Outgrowth and Synaptic Proteins in Magel2-Deficient Mice

This study shows that Magel2 deficiency causes reduced neurite outgrowth and glutamatergic synapses, which are partially rescued by postnatal oxytocin treatment in mice.

Characterization and rescue by oxytocin of an atypical thermo-sensory reactivity in neonatal mice lacking the autism-associated gene Magel2.

This study identifies early life thermosensory impairments in Magel2-deficient mice and shows oxytocin treatment can rescue these deficits.

Disruption of the transcription factor NEUROD2 causes an autism syndrome via cell-autonomous defects in cortical projection neurons

This study identifies NEUROD2 mutations linked to ASD and intellectual disability, showing their role in cortical development and function through mouse models.

Correct laminar positioning in the neocortex influences proper dendritic and synaptic development

This study shows that laminar positioning of cortical neurons affects dendritic and synaptic development, with misplaced neurons showing severe defects in dendrite and synapse formation.