CYB5R4 sustains endothelial proliferation and ischemia-induced angiogenesis by maintaining RRM2-dependent nucleotide balance
Shuai Sammy Yuan, Scott A. Hahn, Nicole Colussi, Steven J. Mullett, Stacy L. Gelhaus, Francisco J. Schopfer, Adam C. Straub
This study identifies CYB5R4 as a regulator of endothelial proliferation and ischemia-induced angiogenesis through RRM2-dependent nucleotide balance.
bioRxiv · Sep 17, 2025 · PreprintMolecular Biology