Steven J. Mullett

The paper shows that dissociation of mitochondrial Complex V into Fo and F1 domains balances anabolic and energy needs in cancer cells by uncoupling ATP synthesis from TCA cycle activity.

This study identifies a shared proteomic profile in Alzheimer's disease with and without psychosis and a separate molecular signature linked to postsynaptic density disruption.

This paper shows that intracellular glutamine levels, influenced by nitrogen availability, regulate biofilm formation in Mycobacterium smegmatis by affecting aggregation.

This study identifies CYB5R4 as a regulator of endothelial proliferation and ischemia-induced angiogenesis through RRM2-dependent nucleotide balance.

This study shows Adropin treatment reverses cardiac dysfunction and metabolic defects in a mouse model of HFpEF by reducing O-GlcNAcylation of LCAD and improving fatty acid oxidation.

This study identifies Gcn5l1 as a heart-specific factor that modulates cholesterol metabolism and heart-to-liver crosstalk in cardiometabolic heart failure, revealing the heart's role in systemic metabolic dysfunction.

This study shows that the microbiota influences reproductive lifespan by maintaining the ovarian reserve through short chain fatty acids and gene regulatory networks.

This study shows that TCA cycle dysfunction and amino acid catabolism in mice with HFpEF drive hepatic steatosis similar to human NAFLD.

This paper shows that LXA4 and its 15-oxo metabolite do not activate FPR2 receptor but instead modulate redox-sensitive pathways through electrophilic interactions.

This study shows that microbial circadian rhythms influence sex differences in host gene expression and metabolism, with diet affecting these sex-specific patterns.