Spatially resolved mapping of histones reveal selective neuronal response in Rett syndrome
Frederike Schäfer, Giuseppina De Rocco, Moritz Carl Völker-Albert, Ignasi Forné, Nicoletta Landsberger, Axel Imhof, Shibojyoti Lahiri
This study uses mass spectrometry imaging and laser capture microdissection to analyze histone proteoforms in RTT mouse models, revealing neuron-specific differences and mutation-dependent chromatin changes.
FEBS Journal · Apr 1, 2026Peer-reviewedNeuroscience