Author

Fuquan Zhang

MRC Prion Unit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Christian SchmidtiD· 2 shared Jacqueline M. Linehan· 2 shared John CollingeiD· 2 shared Sebastian BrandneriD· 2 shared Simon MeadiD· 2 shared Aline T. MarinhoiD· 1 shared Andrew Tomlinson· 1 shared Athanasios DimitriadisiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Christian SchmidtORCID

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Author profile →

2 papers

Recent·Most cited

Intracellular Trafficking SNARE Protein, Syntaxin-6, is a Modifier of Prion and Tau Pathogenesis in vivo and in Cellular Models

Elizabeth Hill, Mitali Patel, Juan Manuel Ribes, Jacqueline M. Linehan, Fuquan Zhang, Michael Farmer, Tatiana Jakubcova, Shyma Hamdan, Andrew Tomlinson, Tiziana Ercolani, Christian Schmidt, Parvin Ahmed, George Thirlway, Silvia A. Purro, Fabio Argentina, , Simon Mead

This study identifies syntaxin-6 as a modifier of prion and tau pathogenesis, showing it affects disease onset but not progression in experimental models.

bioRxiv · Feb 19, 2025 · PreprintNeuroscience

Single-nuclei transcriptomics of mammalian prion diseases identifies dynamic gene signatures shared between species

Athanasios Dimitriadis, Fuquan Zhang, Thomas Murphy, Thomas Trainer, Zane Jaunmuktane, Christian Schmidt, Tamsin Nazari, Jacqueline M. Linehan, Sebastian Brandner, John Collinge, Simon Mead, Emmanuelle A. Viré

This study uses single-nuclei transcriptomics to identify dynamic gene signatures in prion diseases across species.

bioRxiv · Sep 13, 2022 · PreprintNeuroscience