Author

Tamsin Nazari

MRC Prion Unit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacqueline M. Linehan· 3 shared John CollingeiD· 3 shared Sebastian BrandneriD· 3 shared Emmanuelle A. ViréiD· 2 shared Michael Farmer· 2 shared Simon MeadiD· 2 shared Adam CaulderiD· 1 shared Athanasios DimitriadisiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersNeuroscience

Jacqueline M. Linehan

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Author profile →

3 papers

Recent·Most cited

Induction and characterisation of Abeta and tau pathology in AppNL-F/NL-F mice following inoculation with Alzheimer's disease brain homogenate

Silvia A. Purro, Michael Farmer, Emma Quarterman, Julia Ravey, David X. Thomas, Elizabeth Noble, Catherine Turnbull, Jacqueline M. Linehan, Tamsin Nazari, Sebastian Brandner, Mark A. Farrow, Dominic M. Walsh, John Collinge

This study inoculates AppNL-F/NL-F mice with AD brain homogenates to study A{beta} and tau pathology, finding prion-like propagation and new insights into their interactions.

bioRxiv · Jul 11, 2024 · PreprintNeuroscience

Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob Disease risk gene Stx6

Emma L. Jones, Elizabeth Hill, Jacqueline M. Linehan, Tamsin Nazari, Adam Caulder, Gemma F. Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin K. Sandberg, Emmanuelle A. Viré, Thomas J. Cunningham, , Simon Mead

This study investigates the role of Stx6 in prion disease by creating a mouse model with genetic depletion of Stx6 and finding a modest effect on prion disease incubation periods.

bioRxiv · Jan 10, 2023 · PreprintNeuroscience

Single-nuclei transcriptomics of mammalian prion diseases identifies dynamic gene signatures shared between species

Athanasios Dimitriadis, Fuquan Zhang, Thomas Murphy, Thomas Trainer, Zane Jaunmuktane, Christian Schmidt, Tamsin Nazari, Jacqueline M. Linehan, Sebastian Brandner, John Collinge, Simon Mead, Emmanuelle A. Viré

This study uses single-nuclei transcriptomics to identify dynamic gene signatures in prion diseases across species.

bioRxiv · Sep 13, 2022 · PreprintNeuroscience