Author

Emmanuelle A. Viré

MRC Prion UnitORCID 0000-0002-7868-9923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jacqueline M. Linehan· 2 shared John CollingeiD· 2 shared Sebastian BrandneriD· 2 shared Simon MeadiD· 2 shared Tamsin Nazari· 2 shared Adam CaulderiD· 1 shared Athanasios DimitriadisiD· 1 shared Christian SchmidtiD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersNeuroscience

Jacqueline M. Linehan

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Author profile →

3 papers

Recent·Most cited

Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob Disease risk gene Stx6

Emma L. Jones, Elizabeth Hill, Jacqueline M. Linehan, Tamsin Nazari, Adam Caulder, Gemma F. Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin K. Sandberg, Emmanuelle A. Viré, Thomas J. Cunningham, , Simon Mead

This study investigates the role of Stx6 in prion disease by creating a mouse model with genetic depletion of Stx6 and finding a modest effect on prion disease incubation periods.

bioRxiv · Jan 10, 2023 · PreprintNeuroscience

Epigenetic age acceleration is associated with oligodendrocyte proportions in MSA and control brain tissue

Megha N. Murthy, Gemma L. Shireby, Yasuo Miki, Emmanuelle A. Viré, Tammaryn Lashley, Thomas T. Warner, Jonathan S. Mill, Conceição Bettencourt

The paper investigates epigenetic age acceleration in white matter of MSA and control brains, finding that oligodendrocyte proportions influence age acceleration.

Neuropathology and Applied Neurobiology · Dec 21, 2022Peer-reviewedNeuroscience

Single-nuclei transcriptomics of mammalian prion diseases identifies dynamic gene signatures shared between species

Athanasios Dimitriadis, Fuquan Zhang, Thomas Murphy, Thomas Trainer, Zane Jaunmuktane, Christian Schmidt, Tamsin Nazari, Jacqueline M. Linehan, Sebastian Brandner, John Collinge, Simon Mead, Emmanuelle A. Viré

This study uses single-nuclei transcriptomics to identify dynamic gene signatures in prion diseases across species.

bioRxiv · Sep 13, 2022 · PreprintNeuroscience