Author

K. M. Troike

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. K. A. Neumann· 2 shared D. J. Silver· 2 shared J. Lathia· 2 shared J. M. Brown· 2 shared A. Lauko· 1 shared A. Rabljenovic· 1 shared A. Steffens· 1 shared A. Zalavadia· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

C. K. A. Neumann

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 13, 2022

Tumor cell-intrinsic HFE drives glioblastoma growth

K. M. Troike, D. J. Silver, P. K. Ghosh…·J. Lathia

This study shows that HFE promotes glioblastoma growth by regulating iron homeostasis and oxidative stress, with HFE loss inducing apoptosis and extending survival.

DOI 10.1101/2022.04.13.487917

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 7, 2022

The MIF SNP rs755622 is a germline determinant of tumor immune activation in Glioblastoma

T. Alban, M. M. Grabowski, B. Otvos…·J. Lathia

The paper identifies a germline SNP, rs755622, associated with increased leukocyte infiltration in glioblastoma and links it to lactotransferrin expression as a potential biomarker for immune activation.

DOI 10.1101/2022.03.07.483365

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 8, 2020

Cancer Stem Cell Enrichment and Metabolic Substrate Adaptability are Driven by Hydrogen Sulfide Suppression in Glioblastoma

D. J. Silver, G. A. Roversi, N. Bithi…·J. D. Lathia

A high-fat diet accelerates glioblastoma by inhibiting hydrogen sulfide production, leading to cancer stem cell enrichment and reduced treatment response.

DOI 10.1101/2020.03.08.982116

mousehuman

𝕏 PostBluesky