Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
N. Platt, D. Shepherd, Y. Weng…·F. M. Platt
This study shows that lysosomal Ca2+ release is essential for NLRP3 inflammasome priming and IL-1β production in mice with Niemann-Pick Type C or Tpcn1/Tpcn2 deficiency.
G. C. Churchill, M. Strupp, T. Bremova-Ertl…·A. Galione
This paper shows that N-acetyl-L-leucine is transported by organic anion transporters (OAT) instead of LAT, explaining its drug-like properties compared to L-leucine.
G. C. Churchill, M. Strupp, A. Galione, F. M. Platt
This study investigates the pharmacokinetic differences between enantiomers of N-acetyl-leucine after oral dosing in mice, finding that the D-enantiomer accumulates and has different tissue distribution compared to the L-enantiomer.