Author

G. Carvette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Armstrong· 1 shared A. DiFeo· 1 shared A. Gandhi· 1 shared A. Sobeck· 1 shared C. Nagel· 1 shared C. O'Connor· 1 shared D. Ma· 1 shared D. Thomas· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Armstrong

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1 paper

Recent·Most cited

Small molecule mediated stabilization of PP2A modulates the Homologous Recombination pathway and potentiates DNA damage-induced cell death

R. Avelar, A. Armstrong, G. Carvette, N. Puleo, R. Gupta, J. Colina, P. Joseph, A. Sobeck, C. O'Connor, A. Gandhi, M. Dziubinski, D. Ma, S. Waggoner, K. Zanotti, C. Nagel, , A. DiFeo

This study shows that stabilizing PP2A with a small molecule enhances DNA damage-induced apoptosis in HGSC cells and xenografts, both alone and with PARPi, by inhibiting HR and targeting RAD51.

bioRxiv · Jun 10, 2022Cancer Biology