G. Chopra

Variability of Phenylalanine side chain conformations facilitates promiscuity of Fatty acid binding in Cockroach milk proteins.

This study investigates fatty acid binding specificity and stability of Lili-Mips proteins in the cockroach Diploptera punctata, showing similar affinities for different fatty acids and pH-dependent stability.

One Scaffold - Different Organelles Sensors: pH-Activable Fluorescent Probes for Targeting Live Primary Microglial Cell Organelles

The paper designs pH-activable fluorescent probes with a common scaffold for targeting different organelles in live primary microglial cells, showing differential fluorescence and pKa based on functional group changes.

Integration of Biodynamic Imaging and RNA-seq classifies chemotherapy response in canine diffuse large B-cell lymphoma

This study combines BioDynamic Imaging and RNA-seq data to develop a model predicting chemotherapy response in canine DLBCL by integrating gene expression and phenotypic biomarkers.

Breaking a Strong Amide Bond: Structure and Properties of Dimethylformamidase.

This paper describes the structure and properties of Dimethylformamidase (DMFase) from Paracoccus, revealing new protein folds and a unique mononuclear iron active site that enables its function in harsh conditions.

CANDOCK: Chemical atomic network based hierarchical flexible docking algorithm using generalized statistical potentials

CANDOCK improves small molecule docking by addressing limitations in interaction modeling and conformation sampling, showing better correlation between docking scores and experimental binding affinities.

Stable and Reversible Functionalization of the Native Phosphate Groups on Live Cells

This paper introduces a method to functionalize live cell surfaces using native phosphate groups, enabling stable and reversible labeling without prior cell engineering.