G. Dellaire

SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML

This study shows SUMO promotes DNA repair protein collaboration for telomere maintenance in ALT cancer cells without PML bodies.

Exploring the interactome of PML nuclear subdomains during fatty acid stress using APEX2-mediated proximity labeling

The paper uses APEX2 proximity labeling to identify the PML nuclear subdomain interactome under fatty acid stress, revealing COPII proteins and other factors involved in lipid stress responses.

Pandemic danger to the deep: the risk of marine mammals contracting SARS-CoV-2 from wastewater

The paper models the risk of marine mammals contracting SARS-CoV-2 from untreated wastewater, highlighting vulnerable species and locations in Alaska.

Lipid-associated PML domains regulate CCTα, Lipin1 and lipid homeostasis

The paper shows that LAP domains in nLDs regulate CCTα, Lipin1, and lipid homeostasis by controlling their recruitment to nLDs.

Haploinsufficient tumour suppressor PRP4K is negatively regulated during epithelial-to-mesenchymal transition

This study shows PRP4K is a haploinsufficient tumor suppressor whose levels are reduced during EMT, promoting invasion without full EMT in mammary cells.

Novel strand exchange activity of the human PALB2 DNA Binding Domain and its critical role for DNA repair in cells

The paper identifies a DNA-binding domain in PALB2 that enhances RAD51-mediated DNA repair and can promote strand exchange independently of RAD51.