Author

G. Farrugia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

A. Beyder· 2 shared L. M. Cowan· 2 shared P. R. Strege· 2 shared A. Mazzone· 1 shared C. A. Ahern· 1 shared C. Alcaino· 1 shared L. S. Milescu· 1 shared O. S. Andersen· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersPhysiology

A. Beyder

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2 papers

Recent·Most cited

Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

P. R. Strege, L. M. Cowan, C. Alcaino, A. Mazzone, C. A. Ahern, L. S. Milescu, G. Farrugia, A. Beyder

This study investigates the mechanosensitivity of NaChBac, a prokaryotic sodium channel, showing that force-induced pore opening, not voltage sensor activation, drives its response to mechanical stress.

bioRxiv · May 10, 2022Physiology

Capsaicin alters human NaV1.5 mechanosensitivity

L. M. Cowan, P. R. Strege, R. Rusinova, O. S. Andersen, A. Beyder, G. Farrugia

This study shows capsaicin reduces NaV1.5 mechanosensitivity in human cells by blocking force-induced changes in sodium current parameters and voltage-dependent behavior.

bioRxiv · Jul 13, 2021 · PreprintBiophysics