Author

A. Beyder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:electrophysiology· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

G. Farrugia· 2 shared L. M. Cowan· 2 shared P. R. Strege· 2 shared A. Mazzone· 1 shared C. A. Ahern· 1 shared C. Alcaino· 1 shared F. T. Chebib· 1 shared G. Nelson· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

G. Farrugia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Activation of PIEZO1 Inhibits Kidney Cystogenesis

Q. Fan, M. Hadla, Z. Peterson, G. Nelson, H. Ye, X. Wang, J.-M. Mardirossian, P. C. Harris, S. L. Alper, P. Y.S., A. Beyder, V. E. Torres, F. T. Chebib

This study shows that activating PIEZO1 reduces cyst formation in kidney cells and ex vivo models, suggesting it could be a therapeutic target for ADPKD.

bioRxiv · May 11, 2024Cell Biology

Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

P. R. Strege, L. M. Cowan, C. Alcaino, A. Mazzone, C. A. Ahern, L. S. Milescu, G. Farrugia, A. Beyder

This study investigates the mechanosensitivity of NaChBac, a prokaryotic sodium channel, showing that force-induced pore opening, not voltage sensor activation, drives its response to mechanical stress.

bioRxiv · May 10, 2022Physiology

Capsaicin alters human NaV1.5 mechanosensitivity

L. M. Cowan, P. R. Strege, R. Rusinova, O. S. Andersen, A. Beyder, G. Farrugia

This study shows capsaicin reduces NaV1.5 mechanosensitivity in human cells by blocking force-induced changes in sodium current parameters and voltage-dependent behavior.

bioRxiv · Jul 13, 2021 · PreprintBiophysics