Author

G. Filaci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Grifoni· 3 shared A. Sette· 3 shared A. Tarke· 3 shared J. M. Dan· 3 shared D. Weiskopf· 2 shared E. Phillips· 2 shared J. Sidney· 2 shared N. Methot· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Grifoni

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3 papers

Recent·Most cited

Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

A. Tarke, Y. Zhang, N. Methot, T. N. Narowski, E. Phillips, S. Mallal, A. Frazier, G. Filaci, D. Weiskopf, J. M. Dan, P. Lakshmanane, R. H. Scheuermann, A. Sette, A. Grifoni

This study identifies T cell epitopes and cross-reactivity patterns across common cold coronaviruses, highlighting conservation and limitations in cross-reactivity among subgenera.

bioRxiv · Jan 4, 2023Immunology

Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

A. Grifoni, Y. Zhang, A. Tarke, J. Sidney, P. Rubiro, M. Reina-Campos, G. Filaci, J. M. Dan, R. H. Scheuermann, A. Sette

The paper predicts MPXV T cell epitopes using VACV epitope data and identifies immunodominant targets to design peptide pools for detecting cross-reactive T cells in vaccinated individuals.

bioRxiv · Sep 6, 2022 · PreprintImmunology

SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron

A. Tarke, C. H. Coelho, Z. Zhang, J. M. Dan, E. D. Yu, N. Methot, N. I. Bloom, B. Goodwin, E. Phillips, S. Mallal, J. Sidney, G. Filaci, D. Weiskopf, R. da Silva Antunes, S. Crotty, , A. Sette

This study shows that SARS-CoV-2 vaccines induce T cell responses that cross-recognize variants from Alpha to Omicron, with high preservation of CD4+ and CD8+ T cell epitopes.

bioRxiv · Dec 28, 2021 · PreprintImmunology