ImmunologybioRxivPreprint
CARD8 inflammasome mediates pyroptosis of HIV-1-infected cells by sensing viral protease activity
Q. Wang, H. Gao, K. M. Clark…·L. Shan
This study identifies CARD8 as a sensor of HIV-1 protease activity, triggering pyroptosis of infected cells and clearing latent HIV-1 in CD4+ T cells.
DOI 10.1101/2020.09.25.308734