Author

G. Hilzenrat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

D. J. Nieves· 3 shared K. Gaus· 3 shared Z. Yang· 2 shared E. Pandzic· 1 shared H. H. MacRae· 1 shared J. F. Berengut· 1 shared J. Goyette· 1 shared J. J. Gooding· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiophysics

D. J. Nieves

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

tagPAINT: covalent labelling of genetically encoded protein tags for DNA-PAINT imaging

D. J. Nieves, G. Hilzenrat, J. Tran, Z. Yang, H. H. MacRae, M. A. B. Baker, J. J. Gooding, K. Gaus

The paper introduces tagPAINT, a covalent labeling method for DNA-PAINT imaging using genetically encoded protein tags, and applies it to study T-cell receptor signaling proteins.

bioRxiv · Jul 29, 2019Biophysics

Stoichiometric quantification of spatially dense assemblies with qPAINT

M. Baker, D. J. Nieves, G. Hilzenrat, J. F. Berengut, K. Gaus, L. K. Lee

This paper demonstrates that qPAINT measurements remain robust even when target molecules are as close as 3 nm apart, showing no significant cross-reactivity in dense assemblies.

bioRxiv · Jan 21, 2019Biophysics

Conformational states control Lck switching between free and confined diffusion modes in T cells

G. Hilzenrat, E. Pandzic, Z. Yang, D. J. Nieves, J. Goyette, J. Rossy, K. Gaus

This study shows that Lck's conformational states determine its diffusive behavior in T cells, with open conformations leading to confined diffusion and closed conformations allowing free diffusion.

bioRxiv · Oct 18, 2018Immunology