Author

G. K. H. Siu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. T. M. Chan· 2 shared H.-Y. Lao· 2 shared K. K.-G. Tam· 2 shared R. Rajwani· 2 shared T. T. L. Ng· 2 shared W.-C. Yam· 2 shared A. K. L. Wu· 1 shared A. W.-t. Lee· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

C. T. M. Chan

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 5, 2021

Construction of lux-based promoter-reporter platforms in Mycobacterium bovis BCG for screening of drug repurposing small-molecule compounds as new anti-tuberculosis drugs

L. Zhu, A. W.-t. Lee, K. K.-L. WU…·G. K. H. Siu

This study constructs a lux-based promoter-reporter system to screen small-molecule compounds for anti-TB activity, identifying one antibiotic and two anti-virulence agents.

DOI 10.1101/2021.11.05.467536

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivAug 16, 2021

The clinical utility of two high-throughput 16S rRNA gene sequencing workflows for taxonomic assignment of unidentifiable bacterial pathogens in MALDI-TOF MS

H.-Y. Lao, T. T. L. Ng, R. Y. L. Wong…·G. K. H. Siu

This study compares two 16S rRNA gene sequencing workflows for identifying unidentifiable bacterial pathogens, finding that the Nanopore workflow offers higher taxonomic resolution and diagnostic accuracy than Illumina.

DOI 10.1128/jcm.01769-21

metagenomicsdeep learning

𝕏 PostBluesky

MicrobiologyClinical ChemistryPeer-reviewedMay 2, 2020

Targeted Sequencing Workflows for Comprehensive Drug Resistance Profiling of Mycobacterium tuberculosis cultures using Illumina MiSeq and Nanopore MinION: Comparison of analytical and diagnostic performance, turnaround time and cost

K. Tafess, T. T. L. Ng, H. Y. Lao…·G. K. H. Siu

This paper compares two sequencing workflows for drug resistance profiling of M. tuberculosis using Illumina MiSeq and Nanopore MinION, finding comparable accuracy with differences in speed and cost.

DOI 10.1093/clinchem/hvaa092

humanwhole-genome sequencing

𝕏 PostBluesky