Author

H.-Y. Lao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:metagenomics· 2 Organism:mouse· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

T. T.-L. NG· 3 shared A. W.-T. Lee· 2 shared C. T. M. Chan· 2 shared G. K. H. Siu· 2 shared G. K.-H. SIU· 2 shared A. C.-Y. Lee· 1 shared A. J. Zhang· 1 shared A. K. L. Wu· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

T. T.-L. NG

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Comprehensive Identification of Pathogenic Microbes and Antimicrobial Resistance Genes in Food Products Using Nanopore Sequencing-Based Metagenomics

A. W.-T. Lee, I. C.-F. NG, E. Y.-K. WONG, I. T.-F. WONG, R. P.-P. SZE, K.-Y. CHAN, T.-Y. SO, Z. ZHANG, S. K.-Y. FUNG, S. C.-Y. WONG, W.-Y. TAM, H.-Y. Lao, L.-K. LEE, J. S.-L. LEUNG, C. T.-M. CHAN, , G. K.-H. SIU

This study uses nanopore sequencing to identify pathogens and antimicrobial resistance genes in food products, finding high prevalence of certain bacteria and resistance genes in specific food types.

Food Microbiology · Aug 1, 2024Peer-reviewedMicrobiology

Construction of lux-based promoter-reporter platforms in Mycobacterium bovis BCG for screening of drug repurposing small-molecule compounds as new anti-tuberculosis drugs

L. Zhu, A. W.-t. Lee, K. K.-L. WU, P. GAO, K. K.-G. Tam, R. Rajwani, G. C. CHABURTE, T. T.-L. NG, C. T. M. Chan, H.-Y. Lao, W.-C. Yam, R. Y.-T. Kao, G. K. H. Siu

This study constructs a lux-based promoter-reporter system to screen small-molecule compounds for anti-TB activity, identifying one antibiotic and two anti-virulence agents.

bioRxiv · Nov 5, 2021 · PreprintMicrobiology

The clinical utility of two high-throughput 16S rRNA gene sequencing workflows for taxonomic assignment of unidentifiable bacterial pathogens in MALDI-TOF MS

H.-Y. Lao, T. T. L. Ng, R. Y. L. Wong, C. S. T. Wong, C. T. M. Chan, D. S. H. Wong, L. K. Lee, S. H. C. Jim, J. S. L. Leung, H. W. H. Lo, I. T. F. Wong, M. C. Y. YAU, J. Y. Lam, A. K. L. Wu, G. K. H. Siu

This study compares two 16S rRNA gene sequencing workflows for identifying unidentifiable bacterial pathogens, finding that the Nanopore workflow offers higher taxonomic resolution and diagnostic accuracy than Illumina.

bioRxiv · Aug 16, 2021Microbiology

SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission in hamsters

B. W. Y. Mok, C. J. Cremin, S.-Y. Lau, S. Deng, P. Chen, A. J. Zhang, A. C.-Y. Lee, H. Liu, S. Liu, T. T.-L. Ng, H.-Y. Lao, E. L.-K. Lee, K. S.-S. Leung, P. Wang, K. K.-W. To, , H. Chen

This study compares SARS-CoV-2 strains in hamsters, finding that the D614G spike variant shows higher replication and transmission efficiency.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology