Author

G. M. Lord

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:flow cytometry· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

J. F. Neves· 4 shared T. Zabinski· 3 shared A. Hertweck· 2 shared E. Read· 2 shared J. K. Howard· 2 shared J. W. Lo· 2 shared J.-H. Schroeder· 2 shared L. B. Roberts· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersImmunology

J. F. Neves

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD90 is not constitutively expressed in functional innate lymphoid cells

J.-H. Schroeder, G. Beattie, J. W. Lo, T. Zabinski, R. Jenner, N. Powell, J. F. Neves, G. M. Lord

This study shows that CD90 is not consistently expressed on all functional innate lymphoid cells in the gut, with some subsets expressing low or no CD90.

bioRxiv · Dec 11, 2021Immunology

Sustained post-developmental T-bet expression is critical for the maintenance of type 1 innate lymphoid cells in vivo

J.-H. Schroeder, L. B. Roberts, K. Meissl, J. W. Lo, D. Hromadova, K. Hayes, T. Zabinski, E. Read, C. Moreira Heliodoro, R. Reis, J. K. Howard, R. K. Grencis, J. F. Neves, B. Strobl, G. M. Lord

This study shows that sustained T-bet expression is necessary for maintaining intestinal ILC1 in vivo, and ILC1 depletion protects against colitis, suggesting potential therapeutic targeting of T-bet for IBD treatment.

bioRxiv · Jun 5, 2021Immunology

The Th1 cell regulatory circuitry is largely conserved between human and mouse

S. Henderson, V. Pullabhatla, A. Hertweck, E. de Rinaldis, J. Herrero, G. M. Lord, R. G. Jenner

The study compares T-bet target gene regulation between human and mouse, finding most genes are conserved despite species-specific pathogen exposure.

bioRxiv · Jan 11, 2021Immunology

A population of CD4+ T cells with a naive phenotype stably polarized to the TH1 lineage

J. W. P. Lo, M. Vila de Mucha, L. B. Roberts, N. Garrido-Mesa, A. Hertweck, J. F. Neves, E. Stolarczyk, S. Henderson, I. Jackson, J. K. Howard, R. G. Jenner, G. M. Lord

The paper identifies a novel CD4+ T cell population with naive markers that are stably polarized to the TH1 lineage and resistant to repolarization.

bioRxiv · Jul 14, 2020 · PreprintImmunology

ILC1-derived TGFβ1 drives intestinal remodelling

G. M. Jowett, M. D. A. Norman, T. T. L. Yu, P. Rosell Arevalo, D. Hoogland, S. Lust, E. Read, E. Hamrud, N. J. Walters, U. Niazi, M. W. H. Chung, D. Marciano, O. S. Omer, T. Zabinski, D. Danovi, , E. Gentleman

The paper shows ILC1-derived TGFβ1 drives intestinal epithelial crypt expansion and extracellular matrix remodeling in co-cultured organoids.

bioRxiv · Apr 20, 2020Immunology