HB-EGF Signaling is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats
H. Maachi, G. Fergusson, M. Ethier, G. N. Brill, L. S. Katz, L. B. Honig, M. R. Metukuri, D. K. Scott, J. Ghislain, V. Poitout
This study shows HB-EGF signaling is essential for glucose-induced β-cell proliferation in rats, mediated through EGFR and ChREBP pathways.
bioRxiv · Dec 3, 2019Cell Biology