Ubr1-induced selective endo-phagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress
B. B. Wang, H. Xu, S. Isenmann, C. Huang, X. Elorza-Vidal, G. Rychkov, R. Estevez, R. B. Schittenhelm, G. Lukacs, P. M. Apaja
This study identifies Ubr1 as a ubiquitin ligase that promotes endo-phagy/autophagy to protect against endosomal and Ca2+-induced proteostasis stress.
bioRxiv · Oct 5, 2021Biochemistry