Author

P. M. Apaja

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. L. Bain· 1 shared B. B. Wang· 1 shared B. Rashidieh· 1 shared C. A. Stewart· 1 shared C. Huang· 1 shared G. Lukacs· 1 shared G. Rychkov· 1 shared H. Xu· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. L. Bain

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2 papers

Recent·Most cited

Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice

B. Rashidieh, A. L. Bain, S. M. Tria, S. Sharma, C. A. Stewart, J. L. Simmons, P. M. Apaja, P. H. G. Duijf, J. Finnie, K. K. Khanna

This study shows that overexpression of B-Crystallin in mice promotes tumorigenesis and metastasis by enhancing cell survival and inhibiting apoptosis.

bioRxiv · Jul 27, 2022Cancer Biology

Ubr1-induced selective endo-phagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress

B. B. Wang, H. Xu, S. Isenmann, C. Huang, X. Elorza-Vidal, G. Rychkov, R. Estevez, R. B. Schittenhelm, G. Lukacs, P. M. Apaja

This study identifies Ubr1 as a ubiquitin ligase that promotes endo-phagy/autophagy to protect against endosomal and Ca2+-induced proteostasis stress.

bioRxiv · Oct 5, 2021Biochemistry