Author

G. Santilli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Thrasher· 2 shared A. Bateman· 1 shared A. Cavazza· 1 shared A. K. Amaya· 1 shared A. L. McCorkindale· 1 shared A. Naseem· 1 shared A. O. Speak· 1 shared A. Schejtman· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

A. J. Thrasher

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors

A. Westhaus, M. Cabanes-Creus, K. L. Dilworth, E. Zhu, D. Salas Gomez, R. G. Navarro, A. K. Amaya, S. Scott, M. Kwiatek, A. L. McCorkindale, T. E. Hayman, S. Frahm, D. P. Perocheau, B. M. Tran, E. Vincan, , L. Lisowski

This study evaluates six AAV vectors in twelve preclinical liver models to identify the most predictive for AAV capsid selection in human hepatocyte transgene delivery.

bioRxiv · Sep 28, 2022 · PreprintBioengineering

Optimized cell culture conditions promote ex-vivo manipulation and expansion of primitive hematopoietic stem cells for therapeutic gene editing.

R. Rai, W. Vetharoy, A. Naseem, Z. Steinberg, A. J. Thrasher, G. Santilli, A. Cavazza

This study optimizes ex-vivo culture conditions to enhance gene editing efficiency in primitive hematopoietic stem cells while preserving their stemness and enabling expansion.

bioRxiv · Jan 11, 2022 · PreprintBioengineering

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

L. O. Randzavola, P. M. Mortimer, E. C. Garside, E. R. Dufficy, A. Schejtman, G. Roumelioti, L. Yu, M. Pardo, K. Spirohn, C. Tolley, C. Brandt, K. Harcourt, E. Nichols, M. Nahorski, G. Woods, , D. C. Thomas

This study identifies EROS as a chaperone essential for gp91phox maturation and P2X7 receptor function, revealing its role in immune responses and infection resistance.

bioRxiv · Sep 14, 2021Immunology