Author

G. Siuzdak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metabolomics· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

B. Warth· 2 shared C. Johnson· 2 shared H. P. Benton· 2 shared A. Aisporna· 1 shared A. Granados· 1 shared A. Mazurek· 1 shared A. O'Connor· 1 shared A. Palermo· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

B. Warth

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mixed Heavy Metals Stress Induces Global Iron Starvation as Revealed by System Level Multi-Omic Analyses

J. L. Goff, Y. Chen, M. P. Thorgersen, L. T. Hoang, F. L. Poole, E. G. Szink, G. Siuzdak, C. J. Petzold, M. W. W. Adams

The paper investigates the combined effects of eight heavy metals on Bacillus cereus, revealing global iron starvation responses not observed with individual metals.

bioRxiv · Aug 5, 2022 · PreprintMicrobiology

METLIN Neutral Loss Database Enhances Similarity Analysis

G. Siuzdak, A. Aisporna, H. P. Benton, J.-M. Galano, M. Giera

The paper introduces the METLIN neutral loss database to enhance structural similarity analysis of molecules using MS2 data.

bioRxiv · Apr 2, 2021Biochemistry

LipidFinder 2.0: advanced informatics pipeline for lipidomics discovery applications

J. Alvarez-Jarreta, P. Rodrigues, E. Fahy, A. O'Connor, A. Price, C. Gaud, S. Andrews, P. Benton, G. Siuzdak, J. Hawksworth, M. Valdivia, S. Allen, V. O'Donnell

LipidFinder 2.0 improves lipidomics analysis with new modules for artefact filtering, isotope deletion, and FDR assessment, showing better performance than existing tools.

bioRxiv · Aug 16, 2020Biochemistry

Palbociclib and fulvestrant act in synergy to modulate central carbon metabolism in breast cancer cells

B. Warth, A. Palermo, N. Rattray, N. Lee, Z. Zhu, L. Hoang, A. Mazurek, S. Dann, T. VanArsdale, V. Fantin, D. Shields, G. Siuzdak, C. Johnson

This study investigates how palbociclib and fulvestrant affect metabolic pathways in breast cancer cells, finding synergistic effects when combined.

bioRxiv · Jun 16, 2018Biochemistry

Metabolomics reveals that dietary xenoestrogens alter cellular metabolism induced by palbociclib/letrozole combination cancer therapy

B. Warth, P. Raffeiner, A. Granados, T. Huan, M. Fang, E. M. Forsberg, H. P. Benton, L. Goetz, C. Johnson, G. Siuzdak

The paper uses metabolomics to show that dietary xenoestrogens alter cellular metabolism in response to palbociclib/letrozole cancer therapy in MCF-7 cells.

bioRxiv · Oct 31, 2017Cancer Biology