G. T. T. Nguyen

This study analyzes GDAP1 mutations linked to CMT, showing they affect protein stability and conserved intramolecular networks, potentially leading to mitochondrial dysfunction and neuronal degeneration.

This study investigates the structural and biochemical effects of CMT-linked GDAP1 mutations, finding reduced thermal stability and disrupted interaction networks that may impair neuronal function.

The paper determines the crystal structure of the human GDAP1 core domain, identifies a fatty acid ligand, and reveals structural insights into disease-related mutations and oligomerization.