Identification and characterization of a G-quadruplex structure in the pre-core promoter region of hepatitis B virus
V. Meier-Stephenson, M. D. Badmalia, T. Mrozowich, K. C. Lau, S. K. Schultz, D. L. Gemmill, C. Osiowy, G. van Marle, C. S. Coffin, T. R. Patel
This study identifies a conserved G-quadruplex structure in the HBV pre-core promoter region and shows its role in viral replication and potential as a therapeutic target.
bioRxiv · Jan 19, 2021Biophysics