Author

V. Meier-Stephenson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Chen· 1 shared C. Mowat· 1 shared C. Osiowy· 1 shared C. S. Coffin· 1 shared D. L. Gemmill· 1 shared D. N. Doell· 1 shared F. Meier-Stephenson· 1 shared G. van Marle· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Chen

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2 papers

Recent·Most cited

Mechanisms of genomic instability dictate cytosolic DNA composition and dendritic cell mediated anti-tumor immunity

S. R. Mosley, A. Chen, D. N. Doell, S. Choi, C. Mowat, F. Meier-Stephenson, V. Meier-Stephenson, K. Baker

The paper shows that genomic instability in MSI CRCs generates cytosolic DNA that enhances STING activation and anti-tumor immunity via dendritic cells, suggesting improved DNA-based therapies for CIN CRCs.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology

Identification and characterization of a G-quadruplex structure in the pre-core promoter region of hepatitis B virus

V. Meier-Stephenson, M. D. Badmalia, T. Mrozowich, K. C. Lau, S. K. Schultz, D. L. Gemmill, C. Osiowy, G. van Marle, C. S. Coffin, T. R. Patel

This study identifies a conserved G-quadruplex structure in the HBV pre-core promoter region and shows its role in viral replication and potential as a therapeutic target.

bioRxiv · Jan 19, 2021Biophysics