Author

G.-H. Wei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:mechanistic / dynamical model· 2

Frequent Co-Authors

Q. Zhang· 5 shared A. Manninen· 3 shared A. Ahtikoski· 2 shared M. H. Vaarala· 2 shared M. Zhong· 2 shared P. Tian· 2 shared R. Devarajan· 2 shared T. Wenta· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersCancer Biology

Q. Zhang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

C. Lian, C. Zhang, P. Tian, Q. Tan, Y. Wei, Q. Zhang, Z. Wang, Q. Zhang, M. Zhong, L.-Q. Zhou, X. Ke, H. Zhang, Y. Zhu, Z. Li, J. Cheng, G.-H. Wei

This study identifies a noncanonical function of ZMYND11 as an arginine-methylated HNRNPA1 reader that suppresses stress granule formation and tumor progression.

Signal Transduction and Targeted Therapy · Sep 28, 2024Peer-reviewedCancer Biology

RFX6 at locus 6q22 confers metastasis and drug resistance in prostate cancer

M. zhong, P. tian, w. xu, q. zhang, Z. Wang, L. Liang, Q. Zhang, Y. Lu, G.-H. Wei

This study identifies RFX6 at locus 6q22 as a driver of prostate cancer metastasis and drug resistance through epigenetic and genetic mechanisms.

bioRxiv · Jan 8, 2024 · PreprintCancer Biology

TEAD1 regulates ITGA1 and ITGA2 to control prostate cancer progression

S. P. Cruz, Q. Zhang, R. Devarajan, C. Paia, B. Luo, K. Zhang, J. Xia, A. Ahtikoski, M. H. Vaarala, T. Wenta, G.-H. Wei, A. Manninen

This study identifies TEAD1 as a regulator of ITGA1 and ITGA2 in prostate cancer, showing their loss promotes tumor progression via TGFβ1-driven EMT.

bioRxiv · Apr 12, 2023Cancer Biology

Disassembly of hemidesmosomes promotes tumorigenesis in PTEN-negative prostate cancer by targeting plectin into focal adhesions

T. Wenta, A. Schmidt, Q. Zhang, R. Devarajan, P. Singh, X. Yang, A. Ahtikoski, M. H. Vaarala, G.-H. Wei, A. Manninen

This study shows that loss of PTEN and hemidesmosomes in prostate cancer promotes tumorigenesis by activating EGFR/PI3K/Akt and FAK/Src pathways through plectin mislocalization.

bioRxiv · Nov 8, 2021Cancer Biology

Extensive germline-somatic interplay drives prostate cancer through HNF1B co-option of TMPRSS2-ERG

N. Giannareas, Q. Zhang, X. Yang, Y. Tian, P. Zhang, Y. Yang, A. Manninen, L. Wang, G.-H. Wei

This study identifies HNF1B as a key mediator of prostate cancer risk through its interaction with TMPRSS2-ERG fusion, revealing germline-somatic interplay in disease progression.

bioRxiv · Sep 2, 2021 · PreprintCancer Biology

Hydrogen sulfide promotes nodulation and nitrogen fixation in soybean-rhizobia symbiotic system

H. Zou, N.-N. Zhang, Q. Pan, J.-H. Zhang, J. Chen, G.-H. Wei

This study shows that hydrogen sulfide promotes nodulation and nitrogen fixation in soybean-rhizobia symbiosis by upregulating key genes and proteins involved in symbiosis and nitrogen metabolism.

bioRxiv · Jul 12, 2018Plant Biology