Systematic Evaluation of Nasal Immune Cell Sampling and Antigen-specific T cell Detection using Cryopreserved Nasal Swabs
Wesley Huisman, Mark A. Power, Nina Le Bert, Elena Mitsi, Nile Verleur, Lisa A. King, D.W. de Vos, Giovanni E. Loe-Sack-Sioe, Helen R. Wagstaffe, Renate S. Hagedoorn, Iman Satti, Corine H. GeurtsvanKessel, Arnaud Marchant, Pieter Pannus, Mirjam H.M. Heemskerk, , Simon P. Jochems
This study evaluates nasal immune cell sampling methods and antigen-specific T cell detection using cryopreserved nasal swabs, finding that flocked swabs yield more cells and cryopreservation preserves functional T cells.
bioRxiv · Sep 1, 2026 · PreprintImmunology