Author

Helen R. Wagstaffe

Imperial College LondonORCID 0000-0002-4462-7484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher ChiuiD· 2 shared Adlina Chan· 1 shared Alex ManniD· 1 shared Alison Boyers· 1 shared Andreas Tiffeau-MayeriD· 1 shared Andrew G. T. PyoiD· 1 shared Andrew P. CatchpoleiD· 1 shared Arnaud Marchant· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Christopher ChiuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Systematic Evaluation of Nasal Immune Cell Sampling and Antigen-specific T cell Detection using Cryopreserved Nasal Swabs

Wesley Huisman, Mark A. Power, Nina Le Bert, Elena Mitsi, Nile Verleur, Lisa A. King, D.W. de Vos, Giovanni E. Loe-Sack-Sioe, Helen R. Wagstaffe, Renate S. Hagedoorn, Iman Satti, Corine H. GeurtsvanKessel, Arnaud Marchant, Pieter Pannus, Mirjam H.M. Heemskerk, , Simon P. Jochems

This study evaluates nasal immune cell sampling methods and antigen-specific T cell detection using cryopreserved nasal swabs, finding that flocked swabs yield more cells and cryopreservation preserves functional T cells.

bioRxiv · Sep 1, 2026 · PreprintImmunology

Temporal Dynamics of Antigen-Specific T Cell Expansion in Primary SARS-CoV-2 Infection

Andrew G. T. Pyo, Adlina Chan, Joshua Rosenheim, Clare E Thakker, Lucy C. K. Bell, Gayathri Nageswaran, Suzanne Byrne, Ben Killingley, David Scobie, Mariya Kalinova, Alison Boyers, Andrew P. Catchpole, Alex Mann, Rik G.H. Lindeboom, Marko Nikolić, , Benny Chain

The paper quantifies T cell response dynamics during primary SARS-CoV-2 infection, showing clone-intrinsic properties drive clonal kinetics and providing insights for vaccine design.

bioRxiv · Nov 4, 2025 · PreprintBiophysics