Molecular BiologyCell ReportsPeer-reviewed
Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes
Maëva Devoucoux, Victoire Fort, Gabriel Khelifi…·Jacques Côté
This paper characterizes the ZMYND11-MBTD1 fusion protein's role in oncogenesis by mislocalizing the NuA4/TIP60 complex to gene bodies, altering transcription and splicing, particularly of the MYC oncogene.