Author

Gabriel Khelifi

Université LavalORCID 0000-0002-8973-7345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Research Focus:differential expression· 5 Approach:experimental assay· 5 Organism:human· 5 Research Focus:gene regulatory network inference· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2

Frequent Co-Authors

Samer M. I. HusseiniD· 6 shared Victoire FortiD· 4 shared Valérie Watters· 2 shared Akhil Shukla· 1 shared Amélie Fradet‐TurcotteiD· 1 shared András NagyiD· 1 shared Balazs Viktor VargaiD· 1 shared Dwayne G. StupackiD· 1 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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6 shared papersCell Biology

Samer M. I. HusseinORCID

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Author profile →

6 papers

Recent·Most cited

Long-read RNA sequencing identifies non-coding isoform switching as a regulator of cell fate

Victoire Fort, Gabriel Khelifi, Ruicen He, Valérie Watters, Melanie Pye, Nobuko Yamanaka, Marina Gertsenstein, Emeline I. J. Lelong, Jérémy Loehr, Victoria Micha, Jean‐Philippe Lambert, Yojiro Yamanaka, Jeffrey L. Wrana, Samer M. I. Hussein

The paper uses long-read RNA sequencing to identify non-coding isoform switching that regulates cell fate during reprogramming.

Nature Communications · Sep 24, 2026Peer-reviewedCell Biology

Matrix Stiffness-driven FAK Splicing Tunes Cell Mechanosensing

Martial Millet, Juliette Gouhier, Olivier Chancy, Elise Tahon, William David Zakzuk Vivas, Émilie Pic, Gabriel Khelifi, Solange Landreville, Samer M. I. Hussein, Dwayne G. Stupack, François Bordeleau

This study identifies a FAK isoform, FAK{Delta}e4, regulated by matrix stiffness, which influences cell migration, invasion, and mechanosensing.

bioRxiv · Jul 27, 2026 · PreprintCell Biology

Snhg26 long non-coding RNA regulates pluripotent cell states through a SINEB2-derived sequence

Victoire Fort, Gabriel Khelifi, Samer M. I. Hussein

This study identifies Snhg26 lncRNA's role in regulating pluripotent cell states through a SINEB2-derived sequence, showing its interaction with transposable elements.

bioRxiv · May 24, 2026 · PreprintCell Biology

Glioblastoma gene expression-based subtypes have defined metabolomic states

Hélèna L. Denis, Jaelle Merone, Akhil Shukla, Valérie Watters, Victoire Fort, Gabriel Khelifi, Mikalie Lavoie, Line Berthiaume, Félix Rondeau, Emy Beaumont, Karine Michaud, Myreille D’Astous, Stéphan Saïkali, Marc‐Étienne Huot, Étienne Audet‐Walsh, , Samer M. I. Hussein

The paper identifies metabolomic differences between mesenchymal and proneural GBM subtypes using cell lines and metabolomic analyses.

bioRxiv · Sep 5, 2025 · PreprintCancer Biology

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes

Maëva Devoucoux, Victoire Fort, Gabriel Khelifi, Joshua Xu, Nader Alerasool, Maxime Galloy, Nicholas Wong, Gaëlle Bourriquen, Amélie Fradet‐Turcotte, Mikko Taipale, Kristin J. Hope, Samer M. I. Hussein, Jacques Côté

This paper characterizes the ZMYND11-MBTD1 fusion protein's role in oncogenesis by mislocalizing the NuA4/TIP60 complex to gene bodies, altering transcription and splicing, particularly of the MYC oncogene.

Cell Reports · Jun 1, 2022Peer-reviewedMolecular Biology

Signal requirement for cortical potential of transplantable human neuroepithelial stem cells

Balazs Viktor Varga, Maryam Faiz, Helena Pivoňková, Gabriel Khelifi, Huijuan Yang, Shangbang Gao, Emma Linderoth, Mei Zhen, Ragnhildur Thóra Káradóttir, Samer M. I. Hussein, András Nagy

This study identifies six signaling pathways regulating the proliferation and developmental potential of human neuroepithelial stem cells in vitro.

Nature Communications · May 23, 2022Peer-reviewedDevelopmental Biology

Gabriel Khelifi · henhao