Author

Gabriel Thomas Johnson

UCL Queen Square Institute of Neurology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna MallachiD· 1 shared Jennifer M. PocockiD· 1 shared John HardyiD· 1 shared Katharina CoskeriD· 1 shared Rita João GuerreiroiD· 1 shared Thomas M. PiersiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Anna MallachORCID

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1 paper

Recent·Most cited

A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC--derived microglia

Thomas M. Piers, Katharina Cosker, Anna Mallach, Gabriel Thomas Johnson, Rita João Guerreiro, John Hardy, Jennifer M. Pocock

This study shows that TREM2 loss-of-function variants in human iPSC-derived microglia impair metabolic switching and PPARγ/p38MAPK signaling, affecting β-Amyloid phagocytosis.

The FASEB Journal · Dec 23, 2019Peer-reviewedNeuroscience