Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs
Monika Dźwigońska, Patrycja Rosa, Szymon Lipiec, Tomasz Obrębski, Gabriela Smyk, Beata Kaza, Salwador Cyranowski, Aleksandra Ellert‐Miklaszewska, Agata Kominek, Anna R. Malik, Katarzyna Piwocka, Jakub Mieczkowski, Bozena Kaminska, Katarzyna B. Leszczyńska
This study shows hypoxia alters myeloid cell functions in glioblastoma by changing gene expression and chromatin accessibility, affecting immune cell markers and transcription factor regulation.
Cell Reports · Sep 1, 2025Peer-reviewedCancer Biology