Anna R. Malik

This study identifies that phosphorylation of AP2 μ2 subunit by p70S6 kinase modulates its conformational dynamics, enhancing clathrin-mediated endocytosis of receptors.

This study shows hypoxia alters myeloid cell functions in glioblastoma by changing gene expression and chromatin accessibility, affecting immune cell markers and transcription factor regulation.

This study shows that impaired astrocyte stress response to amyloid-beta activates delta secretase, leading to amyloid and tau pathologies in Alzheimer's disease.

The paper shows SorLA restricts TNFα release from microglia, reducing their anti-tumor response and promoting glioma growth.

This study shows apoE4 disrupts sortilin's role in neuronal lipid metabolism and endocannabinoid signaling, contributing to Alzheimer's disease risk.

This study identifies SorCS2 as a regulator of EAAT3 trafficking that protects neurons from oxidative stress and epilepsy-induced damage.