Aleksandra Ellert‐Miklaszewska

Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs

This study shows hypoxia alters myeloid cell functions in glioblastoma by changing gene expression and chromatin accessibility, affecting immune cell markers and transcription factor regulation.

Integration of spatial transcriptomics with immunofluorescence staining reveals spatial heterogeneity and plasticity of astrocytes in experimental glioblastomas

The paper integrates spatial transcriptomics with immunofluorescence to study astrocyte heterogeneity and function in glioblastomas, revealing spatial distribution and interactions within the tumor microenvironment.

Integrin blocking peptide reverses immunosuppression in experimental gliomas and improves anti-PD-1 therapy outcome

This study shows that an integrin-blocking peptide enhances anti-PD-1 therapy in gliomas by reversing immunosuppression and restoring an inflammatory tumor microenvironment.