Author

Tomasz Obrębski

University of WarsawORCID 0000-0001-8137-8774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

Anna R. MalikiD· 3 shared Bozena KaminskaiD· 2 shared Thomas E. WillnowiD· 2 shared Vanessa SchmidtiD· 2 shared Agata KominekiD· 1 shared Aleksandra Ellert‐MiklaszewskaiD· 1 shared Aleksandra G. BilskaiD· 1 shared Anne Mette G. JenseniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Anna R. MalikORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedSep 1, 2025

Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs

Monika Dźwigońska, Patrycja Rosa, Szymon Lipiec…·Katarzyna B. Leszczyńska

This study shows hypoxia alters myeloid cell functions in glioblastoma by changing gene expression and chromatin accessibility, affecting immune cell markers and transcription factor regulation.

5 citations

humanmouse

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 30, 2025

A-beta-induced distress of astrocytes triggers Alzheimer disease pathology through non-canonical delta secretase activity

Vanessa Schmidt, Ewelina Ziemlińska, Tomasz Obrębski…·Anna R. Malik

This study shows that impaired astrocyte stress response to amyloid-beta activates delta secretase, leading to amyloid and tau pathologies in Alzheimer's disease.

1 citation

mouseexperimental assay

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NeuroscienceEMBO ReportsPeer-reviewedMar 18, 2024

SorLA restricts TNFalpha release from microglia to shape glioma-supportive brain microenvironment

Paulina Kamińska, Peter Lund Ovesen, Mateusz Jakiel…·Anna R. Malik

The paper shows SorLA restricts TNFα release from microglia, reducing their anti-tumor response and promoting glioma growth.

10 citations

mousescRNA-seq

𝕏 PostBluesky