Author

Gang Zhen

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Organism:yeast· 1

Frequent Co-Authors

Christine MayriD· 2 shared Buki KwoniD· 1 shared Ellen L. Horste· 1 shared Flora C. Y. LeeiD· 1 shared Jernej UleiD· 1 shared Mervin M. FansleriD· 1 shared Sibylle MitschkaiD· 1 shared Ting CaiiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Christine MayrORCID

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3 papers

Recent·Most cited

Subcytoplasmic location of translation controls protein output

Ellen L. Horste, Mervin M. Fansler, Ting Cai, Xiuzhen Chen, Sibylle Mitschka, Gang Zhen, Flora C. Y. Lee, Jernej Ule, Christine Mayr

The paper shows that subcytoplasmic mRNA localization affects protein output by determining mRNA and protein abundance through compartment-specific translation environments.

Molecular Cell · Dec 1, 2023Peer-reviewedMolecular Biology

Transcription is ubiquitously terminated in thousands of bidirectional termination zones in yeast

Gang Zhen, Buki Kwon

The paper identifies thousands of bidirectional termination zones in yeast genomes, showing they are widely used for transcription termination and influenced by chromatin structure and sequence context.

bioRxiv · Nov 2, 2022 · PreprintBioinformatics

Unstructured mRNAs form multivalent RNA-RNA interactions to generate TIS granule networks

Weirui Ma, Gang Zhen, Wei Xie, Christine Mayr

The paper shows that unstructured mRNAs form RNA-RNA interactions to create TIS granule networks that assist protein folding and co-translational complex formation.

bioRxiv · Feb 14, 2020 · PreprintMolecular Biology