Geoffrey M. Wahl

This study identifies Pcdh20 as a POU2F3 target gene essential for tuft cell microvillus structure, showing its role in maintaining microvillar rigidity and organization.

This study shows that LHPP promotes TNBC growth and metastasis by altering the tumor microenvironment and chemokine signaling.

This study shows that ecDNA mis-segregation leads to micronuclei formation, reduced oncogene transcription, and improved patient survival in neuroblastoma.

The paper maps the molecular programs enabling basal-to-luminal fate switching in mammary epithelial cells using time-resolved single-cell epigenetic and transcriptomic analyses.