Author

George L. Orriss

University of Bristol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:E. coli· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Christiane SchaffitzeliD· 2 shared Imre BergeriD· 2 shared Sathish K.N. YadaviD· 2 shared Burak V. KabasakaliD· 1 shared Günce GöçiD· 1 shared J. MailliotiD· 1 shared Jenn-Yeu Alvin SzetoiD· 1 shared Joshua C. BuftoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

Christiane SchaffitzelORCID

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2 papers

Recent·Most cited

Cryo-EM structure of the FtsH periplasmic domain reveals functional dynamics

Günce Göç, Sathish K.N. Yadav, George L. Orriss, Ufuk Borucu, Imre Berger, Christiane Schaffitzel, Burak V. Kabasakal

The paper reports cryo-EM structures of the Escherichia coli FtsH periplasmic domain, revealing conformational flexibility and its role in substrate translocation.

ACS Chemical Biology · Apr 7, 2026Peer-reviewedBiochemistry

Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2

Jenn-Yeu Alvin Szeto, Mirella Vivoli, J. Mailliot, George L. Orriss, Lingling Sun, Joshua C. Bufton, Kyle T. Powers, Sathish K.N. Yadav, Imre Berger, Christiane Schaffitzel

This study identifies UPF2's RNA-binding and unfolding activities, showing its role in stabilizing single-stranded RNA and supporting NMD factor interactions.

RNA · Apr 17, 2025Peer-reviewedBiochemistry