Ufuk Borucu

The paper reports cryo-EM structures of the Escherichia coli FtsH periplasmic domain, revealing conformational flexibility and its role in substrate translocation.

The paper uses cryo-EM to analyze membrane proteins, revealing unexpected high-resolution structures of ArnA and AcrB instead of the intended FtsH and YidC complex.

This study shows that cargo-sensitive TPR switch in kinesin-1 controls its conformational dynamics by dislocating the TPR shoulder, promoting motor domain activation and microtubule binding.

The paper engineers ADDobody protein scaffolds to generate high-avidity ADDomer super-binders through genetic modification and structural validation.

This paper describes a computational method for designing -helical-barrel proteins with small molecule-binding channels, achieving high expression and structural accuracy in E. coli.

This study investigates how the BriS{Delta} variant of SARS-CoV-2 affects spike structure, function, and infectivity across different cell types.